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Drug Ixifast 200 have composition Cefixime 200 mg, Ixifast is indicated in the treatment of the following infections: Otitis media- Caused by H. Influenzae,  Acute bronchitis, Uncomplicated urinary tract infection

Emycin 250 DHG treatment of respiratory tract infections, gastrointestinal tract infections

ROVAS 1.5M IU treatment of Lower, Upper respiratory tract infections : otitis, sore throat

DESCRIPTION:

Ixifast is the brand name of cefixime a broad-spectrum third generation oral cephalosponn, Cefixime is bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentration. Cefixime is also highly stable in the presence of beta- ladamase enzyme. As a result many organisms resistant to penicillin and some cephalosporin due to the presence of beta-lactamase may be susceptible to cefixime.

IXIFAST 200 - Cefixime 200 mg

COMPOSITION:

Ixifast 200 : Each capsule contains cefixime trihydrate BP equivalent to cefixime 200 mg.

Excipients are Lactose Anhydrous & Magnesium Stearate.

“Carefully read the instruction before use, ask your doctor for further information”

INDICATION:

Ixifast 200 is indicated in the treatment of the following infections.

Otitis media- Caused by H. Influenzae (beta lactamase), Moraxelia catarrhalis mostly beta-lactamase positive Streptococcus pyogenes.

Acute bronchitis & exacerbation of chronic bronchitis- Caused by Strep. pneumonias & H. Influenzae (beta lactamase positive & negative strains) Pharyngitis & tonsillitis- Caused by Streptococcus pyogenes.

Uncomplicated urinary tract infection- Caused by E. coli, Proteus mirabillis. Uncomplicated gonorrhoea (cervical / urethral) – Caused by Neisseria gonorrhoea (penicillinase and non penicillinase producing strains)

DOSAGE AND ADMINISTRATION:

Adult: The recommended dose is 400 mg daily. This may be given as a 400 mg capsule daily or as 200 mg capsule every 12 hours for 7 to 14 days depending on the severity of disease.

Uncomplicated gonococcal (cervical / urethral) infection: A single dose of 400 mg is recommended.

Children: >6 months : 8 mg/ kg daily in 1-2 divided doses.

6 months – 1 year: 75 mg daily

1 – 4 years   : 100 mg daily

5 – 10 years   : 200 mg daily

> 10 years  : same as adult dose

PRECAUTION & WARNING:

The possibitity of the emergence of resistant organisms which might result in over growth should be kept in mind, particularly during prolonged treatment in such use, careful observation of the patient is essential. If super infection occurs during therapy appropriate measures should be taken. Dose adjustment in renal impairment as well as those undergoing continuous ambulatory peritoneal dialysis and hemodialysis, should be monitored carefully. It should also be used with caution in patient with gastrointestinal disease, particularly colitis.

CONTRAINDICATION:

It is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.

SIDE EFFECTS:

Side effects are usually mild and transient in nature. The following adverse reactions have been reported – diarrhoea, loose stool, abdominal pain, dyspepsia, nausea & vomiting. In some cases severe pseudomembranous colitis were identified which occurred dunng or after therapy Besides, skin rash, urticaria, drug fever, pruritus, headache, dizziness, prolongation prothrombin time, elevation of SGPT, SGOT transient elevation of BUN or creatinine.

Inform your doctor in case of any adverse reactions related to drug use”

DRUG INTERACTIONS:

Carbamazepine: Elevated carbamazepine levels have been reported

USE IN PREGNANCY & LACTATION:

Cefixime is pregnancy category-B drug. There are no adequate & well- controlled studies in pregnant women. So it should be used during pregnancy only if clearly needed. It is not known whether it appear in breast milk Consideration should be given to discontinuing temporarily nursing during treatment with this drug.

SPECIFICATION: In house SHELF LIFE: 3 years

STORE: Store at a cool & dry place below 30°C.

Keep out of reach of children.

PACK SIZE: Box containing 1 x 10’s capsule in Alu-Alu blister.

Manufactured by: Navana Pharmaceutical Ltd.

Factory: Rupganj, Narayanganj, Bangladesh Head Office: 3/C Purana Paltan, Dhaka-1000, Bangladesh

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